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Multimodal analgesia (MMA) combines different analgesic methods, such as non-steroidal inflammatory drugs (NSAIDs), acetaminophen, and regional anesthesia techniques, to optimize pain control while minimizing ...
Sevoflurane, a commonly used inhalational anesthetic, has been associated with hepatotoxicity, although reports are often isolated. Cerium oxide nanoparticles (CeOâ‚‚) are effective free radical scavengers with ...
Although neostigmine has been traditionally used for neuromuscular blockade reversal in thoracic surgery, incomplete reversal and potential pulmonary complications remain concerns. However, we did not preclude...
Nerve blocks are effective in reducing postoperative opioid use and enhancing rehabilitation following total knee arthroplasty. However, few studies compare the analgesic efficacy and functional recovery of ad...
Renal disease is a significant cause of morbidity and mortality in children and is uniquely challenging in the anesthetic management of pediatric patients. Perioperative pain management is a core component in ...
Children are at an increased risk of medication errors (MEs) during perioperative care compared to adult patients. This study aimed to critically look at medication errors and determine the frequency of advers...
Remimazolam is a novel ultrashort-acting sedative and anesthetic drug. Numerous recent studies have demonstrated its sedative effect, however, research has yet to be conducted to explore the safety of remimazo...
The current study aimed to investigate which one or certain combinations of preoperative comorbidities were associated with higher risk of postoperative delirium.
Laparoscopic inguinal hernia repair (LIHR) has the characteristics of a clear surgical field and short operation time, but it has high requirements for anesthesia. We investigated the impacts of different dose...
Fascial tissues have been overlooked in the past, and there are only few studies on the thoracolumbar fascia and its treatment methods. The present study aimed to investigate the effectiveness and safety of ul...
The prone position, frequently used in spine surgeries for optimal surgical access, induces physiological changes in cardiovascular and respiratory parameters. Increased intraabdominal and intrathoracic pressu...
To observe the effect of low-dose esketamine combined with propofol in pediatric strabismus surgery.
Various sensory stimuli, including verbal communication, can influence patients' consciousness level, pain perception, and agitation in intensive care units (ICU). This study aimed to explore the impact of ver...
Continuous intercostal nerve block (ICNB) has been shown to offer effective pain relief after minimally invasive direct coronary artery bypass (MIDCAB). The erector spinae plane block (ESPB) could represent a ...
The choice of anaesthetic technique has the potential to exert a significant influence on the perioperative stress response, immune modulation and inflammation which are critical factors in surgical recovery. ...
This study aimed to assess the effects of hydromorphone as an adjuvant to ropivacaine serratus anterior plane block (SAPB) on postoperative analgesia and inflammatory responses in patients undergoing video-ass...
Validating postoperative nausea and vomiting (PONV) severity based on antiemetics prescription can help actively manage PONV by the Rhodes Index of Nausea, Vomiting, and Retching (RINVR) scale but is relativel...
Although intraperitoneal local anesthetics are commonly used following intra-abdominal surgical procedures, the level of evidence supporting their use for postoperative pain management remains uncertain.
This research aims to preliminarily verify the feasibility of utilizing a novel perfluoropropane ultrasound contrast agent (UCA) for observing the spread of drugs within the fascial plane.We demonstrated the f...
Intraoperative penile erection (IPE) is an uncommon yet complex issue, and numerous approaches to achieving detumescence fall short of providing consistently satisfactory outcomes. Esketamine, with its sympath...
General anesthesia (GA) is the most accepted option for category-1 emergency cesarean sections (CSs). A low dose of esketamine has been used as an excellent adjunct to neuraxial anesthesia (NA) with little eff...
Multimodal analgesia is vital for enhanced recovery after upper-abdominal surgery. While both Intrathecal hydromorphone (ITH) and transversus abdominis plane (TAP) block are widely applied in upper-abdominal s...
While propofol remains widely used for endoscopic sedation, its cardiovascular depression and injection pain limitations have prompted exploration of novel agents (remimazolam, ciprofol). This study aimed to c...
One-lung ventilation (OLV) requires a high inspired oxygen concentration (FiO2) to promote oxygenation improvement, yet it increases the risk of postoperative pulmonary complications. Therefore, this study aimed ...
Endoscopic procedures are essential for diagnosing and managing gastrointestinal conditions, often requiring sedation for patient comfort. Propofol is a common choice for outpatient sedation due to its rapid o...
Pediatric patients undergoing upper gastrointestinal (GI) interventions frequently require sedation and analgesia due to the challenges associated with endoscopic probe placement, particularly the gag reflex. ...
Anxiety during anesthesia induction can lead to various negative outcomes and psychological burdens in children undergoing surgery. Nonpharmacological interventions are available for reducing anxiety in this c...
Multimodal analgesia is an important component of Enhanced Recovery After Surgery (ERAS). Transversus abdominis plane (TAP) block helps achieve this pain management in various types of surgeries. To evaluate t...
Etomidate is a short-acting intravenous anesthetic used to induce general anesthesia. However, myoclonus caused by the administration of etomidate is seen in 50–80% of untreated patients. Due to the high preva...
Postoperative hypothermia seems to be a common problem in surgical patients but is easily ignored. This study aimed to identify risk factors for postoperative hypothermia in non-cardiac surgery patients.
Chronic pain patients often experience moderate to severe anxiety and depressive symptoms. Growing evidence supporting dexmedetomidine as a potential treatment for mental health conditions, research on its app...
The Hypotension Prediction Index (HPI) derived using an Acumenâ„¢ arterial pressure transducer can decrease the incidence of intraoperative hypotension and possibly decrease perioperative complications. The HPI ...
The original article was published in BMC Anesthesiology 2023 23:115
Esketamine has been increasingly used as an adjuvant for propofol-based induction. However, the effective esketamine dose for this indication remains unclear. The authors investigated the effect of different i...
Remimazolam (Rm) is a novel ultra-short-acting benzodiazepine used in general anesthesia. However, its application in pediatric general anesthesia remains limited. This study aims to compare the efficacy, safe...
Post-induction hypotension (PIH) is prevalent in elderly surgical patients and associated with adverse outcomes; however, predicting PIH remains challenging. We aimed to develop a feasible and practical PIH pr...
Analgesic treatment is the primary method for managing acute postoperative pain. Opioid analgesics are the main class of drugs used to treat moderate to severe pain, whether it is acute or chronic. These opioi...
Assessing pre-hospital frailty on ICU admission can help in risk stratification. We conducted this prospective, observational study to determine the prevalence of frailty in critically ill patients based on Cl...
The Lancet Commission on Global Surgery highlights perioperative mortality rate (POMR) as a key indicator of a nation’s surgical system effectiveness. While POMR is often measured in high-income countries, it ...
Etomidate-induced myoclonus has become a pressing clinical problem with an incidence of 50–80%. The underlying mechanism involves neocortical glutamate accumulation and N-methyl-d-aspartate (NMDA) receptor act...
Video laryngoscopes are widely used for tracheal intubation, particularly in challenging airway scenarios. The McGrath MAC, AIRWAY SCOPE®, and AceScope® are popular video laryngoscopes with different design featu...
Percutaneous dilatational tracheostomy (PDT) is increasingly used in intensive care units owing to its advantages of reduced surgical trauma and fewer complications. Recently, ultrasonography has become a pote...
The admission of a family member to intensive care represents an emotionally complex experience, often characterised by anxiety, stress and uncertainty. ICU diaries, compiled by nurses and family members, have...
The serratus posterior superior intercostal plane block (SPSIPB) is a newly described truncal block. This study aimed to compare the effects of SPSIPB with conventional methods on postoperative opioid consumpt...
Pain is a protective response to noxious stimuli to prevent further damage. The surgical incision results in several events that lead to pain that outlasts its benefits. Persistent postsurgical pain (PPSP) is ...
Malignant hyperthermia (MH) is a life-threatening autosomal-dominant disorder caused by mutations in the ryanodine receptor 1 (RYR1) gene, leading to calcium dysregulation in skeletal muscle. Patients with gen...
Several Japanese educational institutions have begun to train nurse anesthetists. They manage the patient consistently from pre-operation to post-operation in collaboration with the anesthesiologist. This has ...
Passive smoking is linked to increased respiratory adverse events (AEs) during general anesthesia (GA). This study aims to assess whether females exposed to passive tobacco smoke undergoing GA, experience a hi...
Cold knife conization is usually performed under general anesthesia without intubation. This type of anesthesia is more critical in terms of the properties of the sedative drugs. Remimazolam is a novel ultrash...
Primary graft dysfunction Grade 3 (PGD 3) following lung transplantation significantly increases the incidence of acute and chronic complications. These effects complicate clinical perioperative management and...
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