Fig. 4

MDL-28170 microinjected into the neocortex alleviated etomidate-induced myoclonus and the decrement of KCC2 protein in vivo. Muscular tension monitoring (A), Western blot analysis for KCC2 protein of neocortex (B), and quantification of blot after normalization to α-tubulin of KCC2 (C) in the etomidate plus DMSO, etomidate plus MDL-28170, etomidate plus NMDA, etomidate plus NMDA plus MDL-28170 groups. *: p < 0.05, **: p < 0.01 by one-way multiple comparison ANOVA test