Table 2 Details of study drug administered
Fospropofol (n = 30) | Propofol (n = 30) | P value | |
|---|---|---|---|
Study drug | |||
Duration of study drug infusion, h | 47.50 (31.75 to 48.00) | 48.00 (30.88 to 48.00) | 0.771 |
Dose of study drug, mg/kg/h | 8.19 ± 2.36 | 2.73 ± 0.83 | - |
The reason for the discontinuation of drug | |||
48 h after inclusion | 17 (56.7) | 18 (60.0) | > 0.999 |
Being discharged from ICU | 0 (0.0) | 1 (3.3) | > 0.999 |
The need for an operation under general anesthesia | 4 (13.3) | 2 (6.7) | 0.667 |
No need for deep sedation | 9 (30.0) | 9 (30.0) | > 0.999 |
Dose of remifentanil, µg/kg/h | 5.94 ± 0.29 | 6.01 ± 0.20 | 0.321 |
Midazolam for rescue sedation | 1 (3.3) | 0 (0.0) | > 0.999 |
Duration of norepinephrine infusion, h | 29.25 (12.75 to 46.75) | 41.50 (7.50 to 48.00) | 0.619 |
Maximal dose of norepinephrine from nursing charts, µg/kg/h | 0.28 (0.06 to 0.96) | 0.33 (0.08 to 0.88) | 0.458 |