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Table 3 Comparison of patient characteristics for African American race and all other races combined for cases in which patients received additional reversal with Sugammadex

From: Risk factors for administration of additional neuromuscular block reversal in adults undergoing general anaesthesia: a single centre retrospective case-control study

 

All Others

n = 1282

African American

N = 378

P Value

Age (years) (median [IQR])

63.1 [51.6, 72.1]

58.2 [48.8, 67.3]

< 0.001

Body mass index (kg/m2) (median [IQR])

30.08 [25.92, 35.19]

29.70 [25.66, 36.26]

0.95

ASA 1 or 2, n (%)

209 (16.3)

63 (16.7)

0.886

ASA 3

850 (66.3)

238 (63.0)

0.582

ASA 4

223 (17.4)

77 (20.4)

0.274

Inpatient (%)

429 (33.5)

135 (35.7)

0.453

Emergency case status, n (%)

284 (22.2)

111 (29.4)

0.005

Female, n (%)

602 (47.0)

175 (46.3)

0.867

Neuromuscular disease, n (%)

14 (1.1)

8 (2.1)

0.202

After hours cases, n (%)

94 (7.3)

41 (10.8)

0.037

End stage renal disease, n (%)

24 (1.9)

14 (3.7)

0.058

Case duration (min) (median [IQR])

169 [117, 252]

158 [108, 238]

0.261

Train of four

  

0.459

0 or 1, n (%)

530 (41.3)

165 (43.6)

 

2, 3, or 4

752 (58.7)

213 (56.3)

 

Surgical procedure types

  

0.084

Abdominal/General surgery

436 (34.0)

143 (37.8)

 

Burn surgery

13 (1.0)

2 (0.5)

 

Cardiac surgery

6 (0.5)

1 (0.3)

 

ENT surgery

117 (9.1)

31 (8.2)

 

Neurosurgery

62 (4.8)

6 (1.6)

 

Non-operating room anaesthesia

46 (3.6)

12 (3.2)

 

Orthopedic surgery

212 (16.5)

70 (18.5)

 

Plastic surgery

79 (6.2)

20 (5.3)

 

Thoracic surgery

67 (5.2)

12 (3.2)

 

Urogynecologic surgery

194 (15.1)

57 (15.1)

 

Vascular surgery

43 (3.4)

20 (5.3)

 

Other surgical procedures

7 (0.5)

4 (1.1)

 

Total rocuronium dose mg/kg/hr

0.48 [0.36, 0.67]

0.48 [0.36, 0.65]

0.876

Rocuronium redosed, n (%)

1012 (78.9)

277 (73.3)

0.024

Rocuronium dose > 0.43 mg/kg/hr (%)

1029 ( 60.0)

228( 60.3)

0.683

Primary reversal with neostigmine < 48 min after last dose of rocuronium

756 (63.3)

212 (56.1)

0.013

Neostigmine dose (mg/kg) (median [IQR])

0.05 [0.05, 0.06]

0.05 [0.04, 0.06]

0.588

Time between neostigmine and

sugammadex (min) (median [IQR])

12 [8, 18]

12 [7, 17]

0.103

Time between sugammadex and extubation (min) (median [IQR])

2 [1, 4]

2 [1, 5]

< 0.001

  1. ASA, American Society of Anesthesiologists physical status; IQR, interquartile range