Table 3 Change of Lymphocyte subpopulations from surgery to postoperative day 1 (as percentual change from baseline)
Parameter | Deep anesthesia (target BIS 35 ± 5) (%) | Superficial anesthesia (target BIS 55 ± 5) (%) | Significance level p (* ≤ 0.1 between groups) |
|---|---|---|---|
Number (n) | 8 | 8 | |
CD3⁺(T-cells, mean ± SD) | −4.96 ± 16.01 | −11.39 ± 14.09 | 0.5628 |
CD3‾CD19⁺(B-cells, mean ± SD) | −11.91 ± 16.23 | 6.05 ± 32.34 | 0.2472 |
CD3⁺CD4⁺ (T-helper-cells, mean ± SD) | −3.34 ± 14.83 | −3.61 ± 14.02 | 0.9163 |
CD3⁺CD8⁺ (cytotoxic T-cells, mean ± SD) | −6.04 ± 18.35 | −27.39 ± 13.12 | 0.0209* |
CD3‾CD16⁺CD56⁺ (NK-cells, mean ± SD) | −34.71 ± 33.37 | −31.78 ± 36.36 | 1.0000 |
CD3⁺HLADR⁺ (activated T-cells, mean ± SD) | −9.2 ± 22.61 | −23.88 ± 8.49 | 0.1722 |
CD3‾HLADR⁺ (activated B-cells, mean ± SD) | −14.89 ± 16.18 | 2.96 ± 21.58 | 0.0929* |
CD127⁺ (regulatory T-Cells I, mean ± SD) | −16.29 ± 13.58 | −12.16 ± 20.65 | 0.8480 |
CD25⁺ (regulatory T-cells II, mean ± SD) | −6.27 ± 25.01 | −17.66 ± 16.62 | 0.4062 |