Fig. 2

a Relative changes of lymphocyte subtypes over time- Natural Killer – cells. NK-cells were reduced by more than half after deep anesthesia. T0 – prior to anesthesia, T1 – immediately after anesthesia (approx. 120 min), T2 after reconvalescence (more than 3 month), BIS-bispectral index. *significant from T0 to T1, Mann Whitney U-test (b) Relative changes of lymphocyte subtypes over time- activated B-cells. Activated B-cells were reduced following deep anesthesia. T0 – prior to anesthesia, T1 – immediately after anesthesia (approx. 120 min), T2 after reconvalescence (3 month and more) * significant from T0 to T1 (red), from T1 to T2 (blue), Mann Whitney U-test. (c) Relative changes of lymphocyte subtypes over time- regulatory T-cells. Regulatory T-cells were reduced following deep anesthesia. T0 – prior to anesthesia, T1 – immediately after anesthesia (approx. 120 min), T2 after reconvalescence (3 month and more) * significant from T0 to T1, Mann Whitney U-test