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Table 4 Clinical presentation of patients with sepsis-induced ARDS upon their admission into ICU

From: Dexmedetomidine administration is associated with reduced mortality in patients with sepsis-induced acute respiratory distress syndrome: a retrospective study

 

Control (n = 102)

DEX (n = 106)

p

Hematological parameters

   

 White blood cells, ×109/L

10.7 (7.3–15.4)

12.4 (8.1–18.4)

0.072

 Neutrophils, ×109/L

8.9 (5.7–13.2)

10.5 (6.9–16.1)

0.032

 Lymphocytes, ×109/L

1.0 (0.7–1.5)

1.1 (0.5–1.4)

0.617

 Red blood cells, ×1012/L

3.6 (3.1-4.0)

3.8 (3.3–4.3)

0.040

 Hemoglobin, g/L

111.5 (96.8-125.5)

108.0 (95.8-127.5)

0.765

 Platelets, ×109/L

157.0 (108.8-217.5)

162.5 (118.8-226.3)

0.670

 CRP, mg/L

57.1 (21.1–93.1)

77.0 (20.3–138.0)

0.031

 PCT, ng/mL

18.6 (10.2–22.7)

22.8 (18.6–27.4)

0.001

 IL-1β, pg/mL

97.5 (58.3-108.3)

99.2 (89.4-106.9)

0.176

ABG profiles

   

 pH

7.27 (7.23–7.31)

7.30 (7.20–7.30)

0.001

 Base excess, mmol/L

-3.5 (-7.5-1.9)

-5.6 (-8.2-1.7)

0.118

 aHCO3−, mmol/L

20.8 (17.8–25.1)

20.9 (19.3–26.6)

0.147

 PaCO2, mmHg

50.3 (47.3–56.8)

51.5 (42.6–55.9)

0.237

 PaO2, mmHg

62.4 (57.4–67.6)

64.2 (60.8–70.1)

0.007

 SO2, %

92.0 (87.0–93.0)

93.0 (91.0–96.0)

0.001

 PaO2/FiO2, mmHg

216.2 (199.1-241.6)

217.9 (205.1-235.9)

0.598

 aADO2, mmHg

107.3 (89.5-145.3)

92.0 (75.0-126.5)

0.002

 tHb, g/dL

9.2 (8.4–10.2)

9.3 (8.7–10.3)

0.653

 HbO2, %

85.4 (80.7–87.9)

88.4 (85.9–90.4)

0.001

 MetHb, mmHg

0.3 (0.3–0.5)

0.5 (0.3–0.6)

0.001

  1. Abbreviations: Actual bicarbonate, [aHCO3−]; PaCO2, partial pressure of carbon dioxide; PaO2, partial pressure of oxygen; SO2, oxygen saturation; PaO2/FiO2, oxygenation index; aADO2, alveolar-arterial oxygen pressure; tHb, total hemoglobin; HbO2, oxygenated hemoglobin; MetHb, methemoglobin