| Control (n = 102) | DEX (n = 106) | p |
---|---|---|---|
Prognosis | Â | Â | Â |
 APACHE II score | 22.0 (18.0–25.0) | 20.5 (17.8–25.0) | 0.207 |
 Predicted mortality | 59.7 (50.3–68.7) | 60.2 (48.8–69.5) | 0.640 |
Mechanical ventilation, n. (%) | Â | Â | Â |
 Invasive | 79 (77.5%) | 73 (68.9%) | 0.163 |
 Non-invasive | 25 (24.5%) | 33 (31.1%) | 0.287 |
Sedatives, n. (%) | Â | Â | Â |
 Midazolam | 37 (36.3%) | 27 (25.5%) | 0.092 |
 Propofol | 66 (64.7%) | 88 (83.0%) | 0.003 |
 DEX | 0 (0%) | 106 (100%) | < 0.001 |
Antibiotics, n. (%) | Â | Â | Â |
 Piperacillin/sulbactam | 31 (30.4%) | 20 (18.9%) | 0.053 |
 Ceftazidime | 33 (32.4%) | 35 (33.0%) | 0.918 |
 Imipenem/cilastatin | 46 (45.1%) | 64 (60.4%) | 0.027 |
 Tigecycline | 5 (4.9%) | 34 (32.1%) | < 0.001 |
Corticoids, n. (%) | Â | Â | Â |
 Methylprednisolone | 18 (17.6%) | 23 (21.7%) | 0.464 |
 Hydrocortisone | 8 (7.8%) | 7 (6.6%) | 0.730 |
Outcome, n. (%) | Â | Â | Â |
 MODS incidence | 72 (70.6%) | 60 (56.6%) | 0.036 |
 Actual mortality | 38 (37.3%) | 24 (22.6%) | 0.021 |