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Table 2 Prognostic values, treatment routes and clinical outcomes of patients with sepsis-induced ARDS. Data are presented as n (N%), where n stands for the patient number and N for the percentage in the group

From: Dexmedetomidine administration is associated with reduced mortality in patients with sepsis-induced acute respiratory distress syndrome: a retrospective study

 

Control (n = 102)

DEX (n = 106)

p

Prognosis

   

 APACHE II score

22.0 (18.0–25.0)

20.5 (17.8–25.0)

0.207

 Predicted mortality

59.7 (50.3–68.7)

60.2 (48.8–69.5)

0.640

Mechanical ventilation, n. (%)

   

 Invasive

79 (77.5%)

73 (68.9%)

0.163

 Non-invasive

25 (24.5%)

33 (31.1%)

0.287

Sedatives, n. (%)

   

 Midazolam

37 (36.3%)

27 (25.5%)

0.092

 Propofol

66 (64.7%)

88 (83.0%)

0.003

 DEX

0 (0%)

106 (100%)

< 0.001

Antibiotics, n. (%)

   

 Piperacillin/sulbactam

31 (30.4%)

20 (18.9%)

0.053

 Ceftazidime

33 (32.4%)

35 (33.0%)

0.918

 Imipenem/cilastatin

46 (45.1%)

64 (60.4%)

0.027

 Tigecycline

5 (4.9%)

34 (32.1%)

< 0.001

Corticoids, n. (%)

   

 Methylprednisolone

18 (17.6%)

23 (21.7%)

0.464

 Hydrocortisone

8 (7.8%)

7 (6.6%)

0.730

Outcome, n. (%)

   

 MODS incidence

72 (70.6%)

60 (56.6%)

0.036

 Actual mortality

38 (37.3%)

24 (22.6%)

0.021