Effect of opioid sparing strategies on postoperative pain and perioperative hemodynamics in patients undergoing laparoscopic cholecystectomy: a randomized controlled study

Table 2 Comparison of VAS in different times between three groups

	T1	T2	T3	T4	T5	T6	T7	X²-group effect simple	P
OFA	2(0,4)	2(0,4)	2(1,3)	2(1,3)	1(0,2)	1(0,2)	1(0,1)	99.55	<0.001
OSA	2(0,3)	2(0,3)	2(1,3)	2(1,3)	1(0,2)	1(0,2)	0(0,1)	105.12	<0.001
OBA	2(0,3)	2(1,3)	2(1,3)	3(1,3)	2(1,2)	2(1,2)	1(0,1)	155.43	<0.001
X²-time effect simple	207.96	255.69	292.74	309.50	209.91	175.27	106.43
P	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

Note: Wald X²_group = 7.37, P = 0.025; Wald X²_time = 313.96, P<0.001; Wald X²_time*group=48.12, P<0.001

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