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Table 3 Intraoperative hemodynamic events and rescue drugs. Values are mean ± SD

From: Opioid sparing anesthesia in patients with liver cirrhosis undergoing liver resection: a controlled randomized double-blind study

Variable

Group 1

Opioid sparing (OS)

(n = 46)

Group 2

Opioid based (OB)

(n = 46)

P value

 

Bradycardia incidence intraoperative

6.5%

17.4%

0.11

Hypotension incidence intraoperative

100%

78.3%

Ë‚ 0.001*

Hypertension incidence intraoperative

26.1%

100%

Ë‚ 0.001*

Number of rescue fentanyl doses

0.35 ± 0.48

1.9 ± 0.84

Ë‚ 0.001*

Total rescue fentanyl dose (µg)

25.5 ± 35.98

155.0 ± 69.17

Ë‚ 0.001 *

Number of rescue ephedrine doses

2.4 ± 1.02

1.7 ± 1.24

0.006 *

Total rescue ephedrine dose (mg)

12.1 ± 5.01

8.6 ± 6.18

0.006 *

  1. * = Significant difference between Opioid sparing (OS) and Opioid based (OB)
  2. All variables data were not normally distributed tested by Mann-Whitney test