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Table 2 Intra-operative and ICU fentanyl dose, operative times, ICU and hospital stay. Values are mean ± SD

From: Opioid sparing anesthesia in patients with liver cirrhosis undergoing liver resection: a controlled randomized double-blind study

Variable

Group 1

Opioid sparing (OS)

(n = 46)

Group 2

Opioid based (OB)

(n = 46)

P value

Total intra-operative fentanyl dose (µg)

183.2 ± 35.61

313.5 ± 75.06

Ë‚ 0.001*

Total 1st 48 h ICU fentanyl dose (µg)

354.5 ± 112.62

779.1 ± 294.97

Ë‚ 0.001*

Average end-tidal desflurane (%)

5.3 ± 0.85

8.3 ± 0.70

Ë‚ 0.001*

Duration of anaesthesia (min)

213 ± 86.16

261.1 ± 81.46

0.007 *

Duration of surgery (min)

178.3 ± 81.57

220.5 ± 77.02

0.012 *

Extubation time (min)

10.2 ± 2.69

15.1 ± 3.02

Ë‚ 0.001 *

ICU stay (day)

1.3 ± 0.60

2.1 ± 1.24

0.005 *

Hospital stay (day)

4.9 ± 1.91

6.0 ± 2.61

0.056

  1. * = Significant difference between Opioid sparing (OS) and Opioid based (OB)
  2. ICU = intensive care unit
  3. 1 =data were normally distributed tested by T-test
  4. 2 = data were not normally distributed tested by Mann-Whitney test.