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Table 2 Multivariable logistic regression exploring the impact of UCR on the risk of rapid muscle loss

From: Early urea-to-creatinine ratio to predict rapid muscle loss in critically ill patients with sepsis: a single-center retrospective observational study

 

Adjusted for UCR_D1

Adjusted for UCR_D3

Adjusted for ΔUCR

 

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Age

0.99 (0.97,1.00)

0.03*

0.99 (0.99,1.00)

0.02*

0.99 (0.99,0.99)

0.02*

Male

0.95 (0.58,1.56)

0.85

0.99 (0.61,1.63)

0.98

0.95 (0.58,1.56)

0.99

BMI

0.96 (0.89,1.03)

0.25

0.96 (0.90,1.03)

0.29

0.96 (0.89,1.03)

0.31

SOFA

0.99 (0.94,1.06)

 

0.99 (0.93,1.05)

0.79

0.99 (0.94,1.06)

0.65

L3SMA on Day 1

1.00 (0.99,1.01)

0.76

1.00 (0.99,1.01)

0.86

1.00 (0.98,1.01)

0.89

Lactate

1.00 (0.92,1.09)

0.96

1.02 (0.93,1.11)

0.69

1.00 (0.91,1.09)

0.69

PCT

0.98 (0.95,1.01)

0.16

0.98 (0.95,1.01)

0.22

0.98 (0.95,1.01)

0.13

PNI

0.99 (0.97,1.02)

0.68

0.99 (0.97,1.02)

0.68

0.99 (0.68,1.02)

0.75

UCR_D1

1.00 (0.99,1.01)

0.07

—

—

—

—

UCR_D3

—

—

1.00 (0.99,1.00)

0.61

—

—

ΔUCR

—

—

—

—

1.02 (1.01,1.02)

 < 0.01*

  1. The reference group was non rapid muscle loss. OR odds ratio, CI Confidence interval, SOFA sequential organ failure assessment, BMI body mass index, PCT procalcitonin, PNI prognostic nutritional index, L3SMA skeletal muscle area at L3 slices, UCR urea-to-creatinine ratio, UCR_D1 urea-to-creatinine ratio on day1, UCR_D3 urea-to-creatinine ratio on day3, ΔUCR difference in UCR between day 3 and day 1. *: p < 0 .05