Effect of perioperative methylprednisolone administration on postoperative pleural effusion in older patients with non-small cell lung cancer

Table 3 Association between methylprednisolone and postoperative pneumonia and pleural effusion with logistic regression models and propensity score analysis

	Peural effusion			Pneumonia
Analysis method	OR	95%CI	P value	OR	95%CI	P value
Logistic regression analysis (n = 1,951)
Model 1 (unadjusted model)	0.44	0.34–0.57	< 0.001	1.18	0.87–1.60	0.293
Model 2 (preoperative patient-related covariates adjusted)	0.43	0.33–0.56	< 0.001	1.19	0.88–1.62	0.266
Model 3 (Surgical and anesthetic covariates adjusted)	0.49	0.37–0.65	< 0.001	1.36	0.99–1.88	0.058
Model 4 (all the variables)	0.48	0.36–0.64	< 0.001	1.36	0.99–1.88	0.063
Propensity score analysis (multivariate)
Model PSM (n = 1,476)	0.47	0.35–0.68	< 0.001	1.42	0.92–1.53	0.742

Notes Model 1 was not corrected for any of the covariates. Model 2 was adjusted for patient-related preoperative covariates including demographic information, cumulative comorbidities, and laboratory test indicators. Model 3 was adjusted for surgical anesthesia-related covariates such as surgical site, type of surgery, estimated blood loss. Model 4 was adjusted for all covariates
Abbreviations OR: odd ratio; CI, Confidence Interval

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