Table 2 Patient’s baseline characteristics according to the presence of the perioperative administration of methylprednisolone after propensity score matching analysis
Characteristics | Overall (n = 1476) | Perioperative methylprednisolone | P value | SMD | |
|---|---|---|---|---|---|
No (n = 738) | Yes (n = 738) | ||||
Demographic variables | |||||
 Sex (male/female, %) | 834/642 (56.5/43.5) | 415/323 (56.2/43.8) | 419/319 (56.8/43.2) | 0.875 | 0.011 |
 Age (65–70/≥70 years, %) | 845/631 (57.2/42.8) | 421/317 (57.0/43.0) | 424/314 (57.5/42.5) | 0.916 | 0.008 |
 Surgery duration (< 180/≥180 min, %) | 989/487 (67.0/33.0) | 495/243 (67.1/32.9) | 494/244 (66.9/33.1) | 0.999 | 0.003 |
 BMI (median (IQR)) | 24.39 (22.47, 26.45) | 24.43 (22.46, 26.45) | 24.32 (22.48, 26.43) | 0.876 | 0.013 |
 Smoking (no/yes, %) | 908/568 (61.5/38.5) | 455/283 (61.7/38.3) | 453/285 (61.4/38.6) | 0.957 | 0.006 |
Cumulative comorbidities | |||||
 Hypertension (yes/no, %) | 619/857 (41.9/58.1) | 319/419 (43.2/56.8) | 300/438 (40.7/59.3) | 0.342 | 0.052 |
 Diabetes (yes/no, %) | 329/1147 (22.3/77.7) | 165/573 (22.4/77.6) | 164/574 (22.2/77.8) | 0.993 | 0.003 |
 Coronary heart disease (yes/no, %) | 173/1303 (11.7/88.3) | 86/652 (11.7/88.3) | 87/651 (11.8/88.2) | 0.990 | 0.004 |
 COPD (yes/no, %) | 42/1434 (2.8/97.2) | 21/717 (2.8/97.2) | 21/717 (2.8/97.2) | 0.999 | < 0.001 |
Laboratory indicators | |||||
 Serum albumin (g/L) | 41.3 (39.4, 43.5) | 41.3 (39.3, 43.6) | 41.4 (39.4, 43.0) | 0.886 | 0.007 |
 Hemoglobin (g/L) | 136.0 (127.0, 146.0) | 136.0 (127.0, 146.0) | 136.0 (127.0, 146.0) | 0.708 | 0.012 |
 Leukocyte count (×109/L) | 5.9 (4.6, 6.9) | 5.8 (4.9, 6.9) | 5.9 (4.9, 7.0) | 0.898 | 0.008 |
Perioperative variables | |||||
 ASA (I-II/III-IV, %) | 1285/191 (87.1/12.9) | 643/95 (87.1/12.9) | 642/96 (87.0/13.0) | 0.999 | 0.004 |
 Surgical site (%) |  |  |  | 0.966 | 0.014 |
  Left chest | 609 (41.3) | 302 (40.9) | 307 (41.6) |  |  |
  Right chest | 865 (58.6) | 435 (58.9) | 430 (58.3) |  |  |
  Bilateral | 2 (0.1) | 1 (0.1) | 1 (0.1) |  |  |
 Type of surgery (%) |  |  |  | 0.843 | 0.062 |
  Exploratory operation | 14 (0.9) | 9 (1.2) | 5 (0.7) |  |  |
  Wedge resection | 352 (23.8) | 179 (24.3) | 173 (23.4) |  |  |
  Segmentectomy | 44 (3.0) | 21 (2.8) | 23 (3.1) |  |  |
  Lobectomy | 1023 (69.3) | 508 (68.8) | 515 (69.8) |  |  |
  Pneumonectomy | 43 (2.9) | 21 (2.8) | 22 (3.0) |  |  |
 Lymphadenectomy (yes/no, %) | 1169/307 (79.2/20.8) | 585/153 (79.3/20.7) | 584/154 (79.1/20.9) | 0.998 | 0.003 |
 Open surgery (yes/no, %) | 143/1333 (9.7/90.3) | 68/670 (9.2/90.8) | 75/663 (10.2/89.8) | 0.598 | 0.032 |
 Estimate blood loss (ml) | 50.0 (50.0, 100.0) | 100.0 (50.0, 100.0) | 50.0 (50.0, 100.0) | 0.783 | 0.037 |
 Colloid (ml, median (IQR)) | 500.0 (0.00, 500.0) | 500.0 (0.0, 500.0) | 500.0 (0.0, 500.0) | 0.374 | 0.040 |
 Crystalloid (ml) | 1100.0 (1100.0, 1600.0) | 1100.0 (1100.0, 1600.0) | 1100.0 (1100.0, 1600.0) | 0.176 | 0.001 |
 Blood transfusion (yes/no, %) | 16/1460 (1.1/98.9) | 7/731 (0.9/99.1) | 9/729 (1.2/98.8) | 0.802 | 0.026 |
 Tumor size (cm) | 2.3 (1.5, 3.2) | 2.3 (1.5, 3.0) | 2.3 (1.5, 3.3) | 0.926 | 0.017 |
Outcomes | |||||
Postoperative pleural effusion (yes/no, %) | 206/1270 (14.0/86.0) | 134/604 (18.2/81.8) | 72/666 (9.8/90.2) | < 0.001 | 0.532 |
Postoperative pneumonia (yes/no, %) | 144/1332 (9.8/90.2) | 63/675 (8.5/91.5) | 81/657 (11.0/89.0) | 0.136 | 0.033 |