Table 3 Primary outcomes, secondary outcomes and safety outcomes

Primary outcomes

QOR-15 score

   POD1

125.5[118.3–130.0]

136.5[126.3–139]

-9(-11 - -5)

< 0.001

   POD2

134.5[123.3-146.5]

141.5[125.8–145]

-1(-7-2)

0.523

   POD3

142.5[135–145]

141.5[132–149]

-1(-4-3)

0.577

POD7

142.5[135.3–145]

142[138–149]

-1(-4-1)

0.270

Secondary outcomes

Duration of PACU stay, min

24.8(3.1)

13.2(2.8)

11.60(10.42–12.79)

< 0.001

Time to first out-of-bed, min

94.9(3.2)

63.1(3.1)

31.81 (30.57–33.05)

< 0.001

Length of hospital stay, d

2[2–2]

2[2–2]

0(0–0)

0.849

Sore throat

7(14.6%)

0(0%)

-

0.019

Cough and phlegm

8(16.7%)

1(2.1%)

9.4(1.13–78.41)

0.036

Airway dryness score

   Mouth

   30 min after surgery

5[4.3-6]

3[2–4]

2(1–3)

< 0.001

   1 h after surgery

4[3-5.8]

3.5[2–5]

1(0–1)

0.058

   3 h after surgery

2[2–2]

2[1–2]

0(0–0)

0.096

   Throat

   30 min after surgery

5[4–7]

3[2–4]

2(1–3)

< 0.001

   1 h after surgery

4[3-4.8]

4[3.3-4]

0(0–0)

0.919

   3 h after surgery

2[2-2.8]

2[1–2]

0(0–0)

0.109

Surgeons’ satisfaction

0.504

   Not satisfied

0

0

   Satisfied

6(12.5%)

4(8.3%)

   Totally satisfied

42(87.5%)

44(91.7%)

Safety outcomes

   Hypotension

5(10.4%)

4(8.3%)

0.782(0.197–0.859)

> 0.99

   Bradycardia

3(6.3%)

4(8.3%)

1.364(0.288–6.448)

> 0.99

   Hypertension

1(2.1%)

2(4.2%)

2.043(0.179–23.319)

> 0.99

   Tachycardia

2(4.2%)

3(6.3%)

1.533(0.245–9.614)

> 0.99

Interventions for haemodynamic events

9(18.8%)

7(14.6%)

0.740(0.251–2.180)

0.584

Hypoxemia

2(4.2%)

3(6.25%)

1.53(0.45–9.61)

> 0.99

Sedation in PACU

4(8.3%)

2(4.2%)

0.478(0.083–2.744)

0.673

PONV within 0–48 h

3(6.3%)

2(4.2%)

0.652(0.104–4.089)

> 0.99

Nightmare or hallucination

0(0)

0(0)

-

Delirium

0(0)

0(0)

-