Table 1 Baseline demographic and clinical features in patients with influenza A virus infection at admission
Variables | influenza A virus-non-ARDS (n = 31) | influenza A virus-ARDS (n = 74) | P value |
|---|---|---|---|
Age (years) | 52.61 (± 15.28) | 58.26 (± 15.22) | 0.086 |
Sex (male) | 21 (67.7% ) | 50 (67.6%) | 0.986 |
Active smoking habits, n (%) | 3 (9.7%) | 10 (13.5%) | 0.751 |
Clinical symptoms | |||
Temperature ≥ 39.0℃ | 26 (83.9%) | 64 (86.5%) | 0.727 |
Respiratory rate (per minute) | 22.94 (± 3.97) | 25.15 (± 5.70) | 0.051 |
Dry cough, n (%) | 12 (38.7%) | 17 (23.0%) | 0.100 |
Expectoration, n (%) | 18 (58.1%) | 52 (70.3%) | 0.226 |
Fatigue, n (%) | 17 (54.8%) | 46 (62.2%) | 0.485 |
Sore throat, n (%) | 16 (51.6%) | 47 (63.5%) | 0.256 |
Anorexia, n (%) | 11 (35.5%) | 37 (50.0%) | 0.173 |
Myalgia, n (%) | 5 (16.1%) | 13 (17.6%) | 0.858 |
Dyspnea, n (%) | 13 (41.9%) | 40 (54.1%) | 0.257 |
Comorbidities, n(%) | |||
Hypertension | 9 (29.0%) | 33 (44.6%) | 0.138 |
Diabetes mellitus | 3 (9.7%) | 15 (20.3%) | 0.189 |
Cardiac disease | 0 (0%) | 2 (2.7%) | 0.355 |
Chronic renal disease | 0 (0%) | 1 (1.4%) | 0.515 |
Chronic lung disease | 0 (0%) | 6 (8.2%) | 0.100 |
Chronic liver disease | 0 (0%) | 3 (4.1%) | 0.255 |
Malignancies | 0 (0%) | 3 (4.1%) | 0.553 |
APACHE II score | 10.35 (± 2.18) | 14.00 (± 2.04) | < 0.001 |
SOFA score | 4.48 (± 1.06) | 7.31 (± 2.53) | < 0.001 |
PaO2/FiO2 (mmHg) | 188.45 (± 22.62) | 160.34 (± 30.02) | < 0.001 |