Table 4 Characteristics of ciprofol and propofol

Chemical Formula

C14H20O

(R)-2-(1-cyclopropylethyl)-6-isopropylphenol

C12H18O

2,6-diisopropylphenol

pKa Value

11.8

11.1

Potency Difference

5 more potent than propofol

-

Solution Type

Lipid-in-water solution

Lipid-based solution

Complications

Hypotension, bradycardia, apnea, respiratory depression, hypoxia

Propofol infusion syndrome

Dosage (Adults)

0.4 mg/kg

Typically 1.5–2.5 mg/kg for induction, followed by maintenance infusion rates

Dosage (Children)

-

Typically 1–3 mg/kg for induction, followed by maintenance infusion rates

Cost Difference

1–2 times higher than propofol

Varies depending on the region and brand