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Table 3 The total noradrenaline dose administered at different time points and the total noradrenaline consumption in the 28 days in the three studied groups

From: Comparative study between high and low dose methylene blue infusion in septic cancer patients: a randomized, blinded, controlled study

 

Group A

(n = 30)

Group B

(n = 30)

Group C

(n = 30)

p-value

Post Hoc

Noradrenaline dose (mg)

     

T0

0.39 ± 0.12

0.42 ± 0.12

0.46 ± 0.11

0.076

 

T1

0.42 ± 0.13

0.41 ± 0.13

0.43 ± 0.12

0.713

 

T2

0.42 ± 0.13

0.40 ± 0.12

0.38 ± 0.12

0.533

 

T3

0.43 ± 0.13

0.37 ± 0.12

0.34 ± 0.12

0.022*

p1 = 0.167

p2 = 0.026*

p3 = 0.698

T4

0.39 ± 0.12

0.30 ± 0.13

0.26 ± 0.12

0.002*

p1 = 0.030*

p2 = 0.003*

p3 = 0.636

T5

0.31 ± 0.05

0.14 ± 0.06

0.06 ± 0.10

< 0.000*

p1 < 0.001*

p2 < 0.001*

p3 = 0.284

Total noradrenaline consumption at 28 days (mg)

133.8

(95.7-156.2)

92.9

(83.5–116.0)

82.9

(63.1–116.0)

< 0.001*

p1 = 0.002*

p2 < 0.001*

p3 = 0.751

  1. Data are presented as mean ± SD or median (IQR)
  2. *Significant as p-value < 0.05. p1: Group A vs. Group B, p2: Group A vs. Group C, p3: Group B vs. Group C