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Table 2 Outcomes of methylene blue treatment of the three studied groups

From: Comparative study between high and low dose methylene blue infusion in septic cancer patients: a randomized, blinded, controlled study

 

Group A

(n = 30)

Group B

(n = 30)

Group C

(n = 30)

p-value

Post hoc

Time to vasopressor discontinuation (h)

94.3 ± 17.6

73.6 ± 11.6

70.1 ± 13.4

< 0.001*

p1 < 0.001*

p2 < 0.001*

p3 = 0.644

Vasopressor-free days at 28 days

23 (0–26)

25 (0–26)

25 (0–26)

< 0.001*

p1 < 0.001*

p2 < 0.001*

p3 = 0.891

Mechanical ventilation (days)

5 (1–18)

5 (1–13)

4 (1–10)

0.106

 

ICU length of stay (days)

12 (3–27)

9 (3–19)

8 (3–17)

0.373

 

Hospital stay (days)

27 (3–42)

15 (3–23)

13 (3–22)

0.292

 

Mortality rate

14 (46.7%)

9 (30.0%)

6 (20.0%)

0.083

 

Hazard Ratio (95% CI)

1 (Ref)

0.49 (0.17–1.41)

0.29 (0.09–0.90)

  
  1. Data are presented as mean ± SD, median (range), or frequency (%)
  2. *Significant as p-value < 0.05. p1: Group A vs. Group B, p2: Group A vs. Group C, p3: Group B vs. Group C